Links & Resources
A curated collection of useful resources for organic chemistry researchers, educators, and students.
Reaction Info
Info on reactions (inc. named items), electron pushing, acid/base catalysis, natural pdt. syntheses
- Acronyms (Hans Reich's Collection - DOC)
- Carbonyl Chemistry (Hans Reich's Collection - DOC)
- Electron Pushing/Drawing Mechanisms (Hans Reich's Collection - DOC)
- Total Syntheses Indexed by Named Reactions (Hans Reich's Collection - DOC)
- Named Reagents (Hans Reich's Collection - DOC)
- Named Rules and Effects (Hans Reich's Collection - DOC)
- Organic Reactions
- Organic Syntheses
- Protecting Groups-Organic Chemistry Portal
- Terms used in Physical Organic Chemistry
Reaction Topics
- Acidity and Basicity (Reusch Virtual Textbook)
- Combinatorial Chemistry Review
- Combinatorial Chemistry (at Science Direct)
- Flow Chemistry-Organic Chemistry Portal
- Green Chemistry
- Green Chemistry-Organic Chemistry Portal
- Microwave Syntheses-Organic Chemistry
- Multicomponent Reactions-Organic Chemistry
- Organocatalysis-Organic Chemistry
- Organometallic Chemistry (Hans Reich's Collection - DOC)
- Pericyclic Reactions (Hans Reich's Collection - DOC)
- Photochemistry (Reusch Virtual Textbook)
- Reduction and Oxidation (Hans Reich's Collection - DOC)
- Sonochemistry-Organic Chemistry
Other Sites on Named Reactions
- Name Reaction.com (Toronto, by Endri Gjiri)
- Named Reactions-Organic Chemistry Portal (by Doug Taber)
- Organic Reactions (Wikipedia)
- SynArchive.com (by Daniel Beaudoin)
- Monomerchem, Inc. (by Marcus Brackeen)
- "ReactionFlash™ App" (developed by Elsevier and Prof.Erick M.Carreira, ETH-Zürich)
- ReactionGuessr
Lists of Total Syntheses (Reaction Schemes are included)
- Natural Product Syntheses (Hans Reich's Collection - DOC)
- Totally Synthetic Blog (by Docherty/Taber)
- SynArchive
- Prof. Dirk Trauner (New York University) group's Total syntheses problem sets
- "Synthesis Club Roadmap Problems" by German Cancer Research Center
- "Synthesis Workshop" by Dr. Matthew Horwitz
- University of Utah, Dept of Chemistry Synthesis Club
Chemical Data
Info on pKa values, nucleophile/electrophiles, A-values, solvents, physical constants, etc.
- A-Values (Hans Reich's Collection - DOC)
- Bond Energies and Bond Dissociation Energies (Reusch Virtual Textbook)
- Bond Dissociation Energies (Prof. Armen Zakarian, University of California Santa Barbara)
- Bond Dissociation Energy Estimator by the National Renewable Energy Laboratory (NREL)
- Electronegativities of Elements-Periodic Table (Hans Reich's Collection - DOC)
- pKa Values (Water, DMSO, gas phase) (Hans Reich's Collection - DOC)
- Rowan pKa predictor
- Properties of Common Organic Compounds (Steven Murov)
Nucleophile/Electrophile Reactivity
- Database of Nucleophilicities and Electrophilicities
- Mayr's Reactivity Scales Poster 2020
- Mayr's Reactivity Scales Poster 2016
- Reactivity Scales for Organocatalytic Reactions Poster
Solvents
- Solvent Properties Table
- Solvent properties table reformatted by Dr. Sasha Sundstrom
- Solvent Miscibility table reformatted by Dr. Sasha Sundstrom
- Solvent Miscibility Table
- Solvent Strength Translator
- Solvent Strength Calculator
- Green Chromatography Solvent Selection Tables (Green Chem., 2012,14, 3020; Supplementary Data)
- See the DOC Green Chemistry Page
Periodic Tables
- Web Elements (interactive)
- PTable (interactive)
- PTable (PDF)
- IUPAC
- IUPAC (PDF)
- American Elements (interactive)
- Chemicool (interactive)
- Elements Database (interactive)
- Chemiplus (interactive)
- Resources on Periodic Table (Steven Murov)
- Photophysical Properties of Photosensitizers and Quenchers (Steven Murov)
- Physical Constants
- Physical Constants wall chart (NIST)
- SI Units
- Nomograph (Boiling point vs Pressure, Aldrich)
- Data Conversion
- Frequency - Wavelength - Energy Converter (Reusch Virtual Textbook)
- Chemistry Data Tables (Wired Chemist)
Spectroscopy Resources
Info on: NMR (1H, 13C, 19F 31P, 11B, 77Se), IR, UV, MS spectroscopy and links to spectra databases
General
General NMR
- NMR Spectroscopy (Hans Reich's Collection - DOC)
- NMR Spectroscopy (Reusch Virtual Textbook)
- NMR Supplemental NMR Topics (Reusch Virtual Textbook)
- The Basics of NMR-Hornak (Rochester Institute of Technology)
- NMR Dictionary
- NMR Multiplet Guide-Nowick (UCI)
- Basics of NMR (University of Dundee)
- Dr. Glenn Facey (University of Ottawa) NMR blogs
NMR Data
- 1H NMR Shifts (Hans Reich's Collection - DOC)
- 13C NMR Shifts (Hans Reich's Collection - DOC)
- Coupling: J(H–H) (Hans Reich's Collection - DOC)
- Coupling: J(C–C) and J(C–H) (Hans Reich's Collection - DOC)
- NMR Solvents (Hans Reich's Collection - DOC)
- Cambridge Isotope’s Solvent Table
- NMR Trace Impurities (Organometallics, 2010)
- NMR Trace Impurities (J. Org. Chem., 1997)
Multinuclear NMR Data
- 19F NMR Shift (Hans Reich's Collection - DOC)
- 19F NMR Coupling Constant (Hans Reich's Collection - DOC)
- 19F NMR Spectral Database by Prof. David Vicic (Lehigh University)
- 31P NMR Shift (Hans Reich's Collection - DOC)
- 31P NMR Coupling Constant (Hans Reich's Collection - DOC)
- 11B
- 77Se NMR Shift (Hans Reich's Collection - DOC)
- NMR Periodic Table
Mass Spectroscopy
- MS Spectroscopy (Reusch Virtual Textbook)
- Exact Masses & Isotope Abundance Ratios and Calculators (Reusch Virtual Textbook)
UV Spectroscopy
IR Spectroscopy
Databases of Spectra
- Spectral Database for Organic Compounds (SDBS)
- NMRShiftDB (database of spectra and tools to predict spectra)
- ChemSpider
Problems
Organic Compound Info
Info on naming organic compounds, functional groups, assigning R/S. and organic compound types
Nomenclature
- General Information (Hans Reich's Collection - DOC)
- Functional Groups Summary (Hans Reich's Collection - DOC)
- Named Reagents (Hans Reich's Collection - DOC)
- Reactive Intermediates (Hans Reich's Collection - DOC)
- Acronyms (Hans Reich's Collection - DOC)
- Nitrogen Containing Functional Groups Summary (Hans Reich's Collection - DOC)
- Abbreviations: Journal of Organic Chemistry
- IUPAC (ACDLabs)
- RSC IUPAC Rules (RSC, free registration required)
- IUPAC Compendium of Chemical Terminology (the Gold Book)
- IUPAC Glossary of Class Names of Organic Compounds and Reactive Intermediates 1995
- IUPAC Naming by G.P Moss
Stereochemistry
- Chiral Configurations (Reusch Virtual Textbook)
- IUPAC Rules for the Nomenclature of Organic Chemistry, Section E: Stereochemistry(1974)
- Axial chirality-Wikipedia
- Chirality and Odour Perception
Organometallic Topics
- Organolithium Reagents (Hans Reich's Collection - DOC)
- Organometallic Chemistry General (Reusch Virtual Textbook)
- Organometallic Hypertextbook
Organic Compound Special Types
- Heterocyclic Chemistry (Reusch Virtual Textbook)
- Nitrogen Containing Functional Groups Summary (Hans Reich's Collection - DOC)
- Pesticides
- Polymers (Reusch Virtual Textbook)
- Carbohydrates (Reusch Virtual Textbook)
- Proteins and Amino Acids (Reusch Virtual Textbook)
- Nucleic Acids (Reusch Virtual Textbook)
- Steroids
- Sweeteners
- Aroma Compounds-Wikipedia
- Table of Naturally Occurring PPAPs (Prof. Robert Grossman, University of Kentucky)
- The Online Peptide Guide
Databases
- CAS Source Index (CASSI) Search Tool
- Beyond CASSI
- ChEMBL (RSC)
- Chemical Abstract Service (CAS)
- ChemSpider (RSC)
- ChemSynthesis
- eMolecules (suppliers)
- OSIRIS Property Explorer
- PubChem (NIH)
- RCSB Protein Databank
- Reaxys
- Science of Synthesis
- Unichem
- WolframAlpha: Chemistry
Sites on Some General Info on Organic Compounds
Safety Resources
Links to useful resources for safe operations of organic chemistry laboratories
- Dow Lab Safety Academy
- Lab Safety Institute
- OSHA Occupational Chemistry Database
- Prudent Practices in the Laboratory (Free download, PDF)
- UCLA: Health & Safety
- UC San Diego-Lab Safety Video Links
- Safety Data Sheet (SDS) lookup by ChemInfo
- Safety Data Sheet (SDS) lookup by ChemicalSafety
- Lab Treatment of Waste Chemicals
- Incompatible Chemicals file archived by Dr. Sasha Sundstrom
- Stability of Diazo Compounds and Diazo Transfer Reagents
Chemical Societies and Portals
Links to chemical societies especially those that have a focus on or related to organic chemistry
- American Association for the Advancement of Science
- American Chemical Society
- American Chemical Society, Division of Organic Chemistry
- Canadian Society for Chemistry, Organic Division
- Chemical Institute of Canada
- International Isotope Society
- International Society of Heterocyclic Chemistry
- National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChe)
- North American Catalysis Society
- Royal Society of Chemistry-Organic Division
- The Society of Synthetic Organic Chemistry, Japan
- The World Association of Theoretical and Computational Chemists
- The American Association of Pharmaceutical Scientists
Literature Sources
Links to literature resources (i.e. lists of journals with an organic chemistry focus)
Laboratory Techniques
Links to resources for doing various general laboratory procedures in organic chemistry labs
- Not Voodoo Organic Techniques/Information
- NOP General Techniques
- NOP all Experiments
- ChemSpider Synthetic Procedure Pages
- Organic Syntheses
- "The Schlenk Line Survival Guide" by Dr. Andryj Borys
- Reaction Setup and Safety Videos (University of Dundee)
- Working with Nitrogen Lines
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
- Titration of Organolithium
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
- Transfer of Chemicals Using Syringes
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
- Cooling Baths
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
- Cooling Baths reformatted by Dr. Sasha Sundstrom
- TLC Stains
- Solvent Degassing
- Solvent Degassing by Freeze-Pump-Thaw
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
- Gas Handling
- the Waser group — at EPFL, the Swiss Federal Institute of Technology in Lausanne, Switzerland
Useful Software
Links to software applications that are likely useful for a broad selection of organic chemists
Chemical Drawing Programs
- ChemDraw
- Colorful ChemDraw Collections
- ChemDraw Magic 4
- ChemDraw Magic Tricks: Quick Catalytic Cycles
- ChemDraw Magic 3
- ChemDraw Magic 2
- ChemDraw Magic 1
- All Videos by Pierre Morieux
- ChemDoodle
- MarvinSketch: Structure Drawing Software
Computational Chemistry
Chemical Inventory and/or Electronic Lab Notebook (ELN)
- User Guides
- Original Software by Dr. Felix Rudolphi
- Modified Version by Dr. Khoi Van
- "Sciformation" by Dr. Felix Rudolphi
- "LabCup"
Diagram Drawing Programs
Others
Educational Resources
Links and resources for educators and students in teaching and learning organic chemistry
- Virtual Textbook of Organic Chemistry
- Acronyms (Hans Reich's Collection - DOC)
- ChemTube (3D Organic Chemistry Animations)
- Chemistry by Design-Jón Njarðarson (Arizona)
- Chemical Educational Xchange (by JCE)
- Chimie générale & organiqué-Gérard Dupuis
- Organic Chemistry InfoGraphics-Roman Valiulin
- Determining the product of Substitution or Elimination Reactions-Robert Grossman (Kentucky)
- Drawing Substitution and Elimination Products-Robert Grossman (Kentucky)
- Electron Pushing/Drawing Mechanisms (Hans Reich's Collection - DOC)
- Organic Education Resources (OrganicERs.org cCWCS)
- Polymer Education Guide
- R/S Chemistry-Master Assigning Absolute Stereochemistry-Neil Garg
- Stereochemistry Help-Robert Grossman (Kentucky)
- The Golden Rules of Organic Chemistry
- The Organic Coloring Book by Neil Garg
- The Adult Organic Coloring Book by Neil Garg
- Chemistry Hall
- QR Chem (presentation materials for instructors)-Neil Garg
- ChemInteractive - Mike Casey
Lecture Notes
- "Advanced Organic Chemistry", Prof. David Evans (Harvard)
- "Advanced Organic Chemistry", Eugene Kwan (Harvard)
- Heterocyclic Chemistry" (Prof. Phil Baran, The Scripps Research Institute)
- Organic Chemistry Videos — section for videos.
- "NMR Spectroscopy" (Hans Reich's Collection - DOC)
- "Organic Synthesis", Prof. Andrew Myers (Harvard)
- Open Source Lecture Notes-Bode Research Group (ETH-Zürich)
- "Organometallics" (Prof. M. Christina White, University of Illinois)
- "Organometallic Chemistry" (Hans Reich's Collection - DOC)
- Aliphatic C–H oxidation (Prof. M. Christina White, University of Illinois)
- 'Synthetic Design' (Prof. Dirk Trauner, New York University)
- Sigman Group MLR Short Course (Prof. Matthew Sigman, University of Utah)
Group Meeting Notes
- Baran Group Meetings (The Scripps Research Institute)
- MacMillan Group Meetings (Princeton University)
- Richmond Sarpong Group Meetings (University of California Berkeley)
- Scott Denmark Group Meetings (University of Illinois)
- Ryan Shenvi Group Meetings (The Scripps Research Insititute)
- Brian Stoltz Group Meetings (California Institute of Technology)
Questions and Problem Sets
- Organic Chemistry Problems (Prof. Joseph J. Topczewski, University of Minnesota)
- Organic Chemistry Practice Problems (Reusch Virtual Textbook)
- "ReactionFlash™ App" (developed by Elsevier and Prof.Erick M.Carreira, ETH-Zürich)
- Dave Evans Problem Set Generator
- University of Utah, Dept of Chemistry Synthesis Club
- RealOrganicChemistry Problem Sets
- Prof. Dennis D. Cao — Macalester College
- Chemdle
- Synthordle
Tutorials
Organic Chemistry Videos
Links to collections and individual (significant/historical) videos about organic chemistry-often lectures
Meetings & Conferences
Links to collections and individual meetings and conferences
Other Sites and Resources
Links on topics related to organic chemistry that do not fit in the other categories on this page
- Chemical (Academic) Genealogy Database
- Famous Organic Chemists
- Nobel Prizes in Chemistry on Nobelprize.org
Accessibility, Diversity, Equity, and Inclusion
Chemistry Portals
- Hans Reich's Organic Chemistry Info (Hans Reich's Collection - DOC)
- Organic Chemistry Portal
- Alfa Aesar's Organic Chemistry Resources
MedChem/Pharma Links
- ACS Division of Medicinal Chemistry (MEDI)
- Biospace Pharmaceutical Company News
- FiercePharma Pharmaceutical Company News
- Mayo Clinic
- Drug design online talks (University of Dundee)
- NIH Entrez Search
Research Group Indices
- Organiclinks (Matt McIntosh's List of Organic Research Groups-Now hosted by the DOC)
- Stephen Chamberland's List of PUI Organic Research Groups
- ChemBioLinks List of ChemBio Research Groups (originally developed by Jared Shaw group - UC Davis)
- Peptidelinks by James Nowick-UC Irvine
Other Resource Collections
- Dan Lehnherr’s Chemistry Resources Summary
- "Meta-List of Free Organic Chem Resources" (Prof. Alex Grenning, University of Florida)
- Prof. Dirk Trauner group Resource page
- Prof. Ryan Shenvi group Resource page
- Prof. Richmond Sarpong group Resource page
- Prof. Jérôme Waser group Useful Links page
- Nessa Carson (@SuperScienceGrl) Study Organic Chemistry Online Collection
Internships and Fellowships
ACS Green Chemistry
Industrial Green Chemistry content, curated by the ACS Green Chemistry Institute Pharmaceutical Roundtable. This organization is dedicated to replace unsustainable chemical practices with those that increase the efficiency of chemical industry with respect to waste generation.
Evans Problem Sets
A generator of Organic Chemistry problems, with filters of difficulty and topic, that is sourced from the renowned problem sets of Professor David Evans.
Virtual Organic Textbook
The Virtual Organic Textbook that was originally developed as a resource at Michigan State University and has since become an on-going curation project of the DOC webmasters. We welcome and encourage contributions to the open-source resource for Organic Chemistry education!