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HomeReuschVirtual Textbook Practice ProblemsAssigning CIP Notation 3 - Taxol

Naming Stereogenic Centers in Taxol

A structural formula of the the antitumor agent taxol is displayed below. The eleven chiral centers are labled in magenta.
A 3-D model of this compound is shown to its right. The molecule can be moved by using the mouse and zoomed by the shift key.
The chiral centers of the model may be labeled in a similar fashion by clicking the label button button.
You should provide a C.I.P. configuration for each chiral center, and identify the configuration of the 11-double bond.

Virtual Textbook: Practice Problems — Assigning CIP Notation 3 - Taxol, figure 1
taxol



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Stereogenic Centers in Morphine
Stereogenic Centers in Strychnine

Identify the configuration at each center
Carbon # R S

1
2
3
4
5
7
8
10
13
2'
3'
C=C (E) or (Z)