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HomeReuschVirtual TextbookIntroduction to Synthesis

Introduction to Synthesis

Organic synthesis is the planned construction of a target molecule from simpler starting materials. Select a topic below, or proceed page by page:

Background — why multistep synthesis is a hard problem, and Wöhler's accidental synthesis of urea.
Principles of Synthesis — building the carbon skeleton, functional group strategy, cascade sequences, and the practice problems.
Retrosynthetic Analysis — working a synthesis backwards from the target, with worked examples.
Stereoselective Synthesis — controlling configuration at each stereogenic center.